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Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is a promising tool for regenerative medicine. The fibroblast cells are the most commonly used cell type for this purpose thanks to their easy accessibility. In this study, we used the fibroblast cell line to introduce the main transcription factors (Oct4, Klf4, Sox2) for reprogramming. Controversy to literature, we used a virus-free...