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The extracellular deposition of amyloid β (Aβ) is known to be the fundamental cause of Alzheimer’s disease (AD). Aβ1-42, generated by β-secretases from the amyloid precursor protein (APP), is the main component of neuritic plaque, and the aggregation of this protein is shown to be dependent to an extent on metal ions such as copper and zinc. However, the mechanism by which Cu2+ affects the physicochemical...
Weber-Fechner Law was verified in between distance-headway (f) and car speed (y). Nobody has ever noticed this fact, since the traditional idea in analyses of road traffic flow has neglected the viewpoint of driver's human factor. The present paper will show the Law existence by measurements of T(time-headway) and V for each pair of cars subsequently flowing on road (X = VT). All graphical relationships...
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