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Purpose Cadmium (Cd) causes chick embryo malformation and abnormal extra-embryonic vasculature. This study investigates the effect of Cd on vasculogenesis, quantifies extra-embryonic vascular development following exposure to cadmium acetate (CdAc). Methods After 48 or 60 h incubation, chicks were explanted and treated with 50 µl of 50 µM CdAc or equimolar sodium acetate. Embryos were again incubated...