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Background and Objectives This study evaluated the influence of the polymorphisms G1784C (rs4822063) and A2386G (rs12487736) of SREBP-2 and SCAP genes, respectively, on the response to atorvastatin treatment in a cohort of Chilean subjects with Amerindian background. Methods A total of 142 hypercholesterolemic individuals underwent atorvastatin therapy (10 mg/day/1 month). Serum lipids levels before...
ObjectiveThe objective of this study was to investigate the allelic frequency of the fat mass and obesity‐associated (FTO) gene (rs9939609) and its influences on obesity and metabolic risk biomarkers in a cohort of normal weight and obese Chilean children determining its ethnicity.
MethodsA total of 136 normal weight children and 238 obese children (between 6 and 11 yr old) from an urban setting...
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