Search results for: Amy F. Smith

Items from 1 to 4 out of 4 results

article

Model‐based inference from microvascular measurements: Combining experimental measurements and model predictions using a Bayesian probabilistic approach

Peter M. Rasmussen, Amy F. Smith, Sava Sakadžić, David A. Boas, more

Objective In vivo imaging of the microcirculation and network‐oriented modeling have emerged as powerful means of studying microvascular function and understanding its physiological significance. Network‐oriented modeling may provide the means of summarizing vast amounts of data produced by high‐throughput imaging techniques in terms of key, physiological indices. To estimate such indices with sufficient...

article

Microvascular hemodynamics in the chick chorioallantoic membrane

Amy F. Smith, Bianca Nitzsche, Martin Maibier, Axel R. Pries, more

Microcirculation > 23 > 7 > 512 - 522

Objective The microvasculature of the CAM in the developing chick embryo is characterized by interdigitating arteriolar and venular trees, connected at multiple points along their lengths to a mesh‐like capillary plexus. Theoretical modeling techniques were employed to investigate the resulting hemodynamic characteristics of the CAM. Methods Based on previously obtained anatomical data, a model...

article

Structure‐Based Algorithms for Microvessel Classification

Amy F. Smith, Timothy W. Secomb, Axel R. Pries, Nicolas P. Smith, more

Microcirculation > 22 > 2 > 99 - 108

ObjectiveRecent developments in high‐resolution imaging techniques have enabled digital reconstruction of three‐dimensional sections of microvascular networks down to the capillary scale. To better interpret these large data sets, our goal is to distinguish branching trees of arterioles and venules from capillaries. MethodsTwo novel algorithms are presented for classifying vessels in microvascular...

article

Transmural Variation and Anisotropy of Microvascular Flow Conductivity in the Rat Myocardium

Amy F. Smith, Rebecca J. Shipley, Jack Lee, Gregory B. Sands, more

Annals of Biomedical Engineering > 2014 > 42 > 9 > 1966-1977

Transmural variations in the relationship between structural and fluid transport properties of myocardial capillary networks are determined via continuum modeling approaches using recent three-dimensional (3D) data on the microvascular structure. Specifically, the permeability tensor, which quantifies the inverse of the blood flow resistivity of the capillary network, is computed by volume-averaging...

INFONA - science communication portal

Search results for: Amy F. Smith

Model‐based inference from microvascular measurements: Combining experimental measurements and model predictions using a Bayesian probabilistic approach

Microvascular hemodynamics in the chick chorioallantoic membrane

Structure‐Based Algorithms for Microvessel Classification

Transmural Variation and Anisotropy of Microvascular Flow Conductivity in the Rat Myocardium

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INFONA - science communication portal

Search results for: Amy F. Smith

Model‐based inference from microvascular measurements: Combining experimental measurements and model predictions using a Bayesian probabilistic approach

Microvascular hemodynamics in the chick chorioallantoic membrane

Structure‐Based Algorithms for Microvessel Classification

Transmural Variation and Anisotropy of Microvascular Flow Conductivity in the Rat Myocardium

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