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We present the case of a 77‐year‐old male patient with more than 50 basal cell carcinomas on the head and upper trunk. The patient did not respond to several lines of treatment, including surgery, imiquimod, retinoids, itraconazole and therapy with the hedgehog inhibitor vismodegib. The patient responded well to off‐label therapy with the anti‐programmed death‐1 antibody pembrolizumab after four infusions.
Isolierte Frakturen des Kapitatums in der Koronarebene kommen einerseits selten vor, andererseits sind sie häufig schwierig nativradiologisch zu diagnostizieren. Die Gefahr des Übersehens dieser Verletzung ist mit weitreichenden, langfristigen Konsequenzen allgegenwärtig. Die Kasuistiken zweier Patienten heben die Bedeutung der computertomographischen Schnittbildgebung zur Verifizierung der Frakturen...
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