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Aims Animal studies have demonstrated that decreased vessel density in islets due to reduced expression of islet vascular endothelial growth factor (VEGF) may lead to impaired insulin secretion from β-cells, possibly contributing to type 2 diabetes development. However, no study has demonstrated an association between VEGF expression and vessel density in islets in human subjects with type 2 diabetes...
Aims Vascular endothelial growth factor (VEGF) is a primary mediator of retinal angiogenesis, and higher levels of intraocular VEGF are observed in patients with active proliferative diabetic retinopathy. Meanwhile, whether serum VEGF level is associated with diabetic retinopathy (DR) or not is controversial. Methods To investigate the significance of serum VEGF levels in diabetic patients with...
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