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Search results for: Zsolt Argenyi

Items from 1 to 20 out of 21 results

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article

Appropriate use criteria in dermatopathology: Initial recommendations from the American Society of Dermatopathology

Claudia I. Vidal, Eric A. Armbrect, Aleodor A. Andea, Angela K. Bohlke, more

Journal of Cutaneous Pathology > 45 > 8 > 563 - 580

Background Appropriate use criteria (AUC) provide physicians guidance in test selection, and can affect health care delivery, reimbursement policy and physician decision‐making. Objectives The American Society of Dermatopathology, with input from the American Academy of Dermatology and the College of American Pathologists, sought to develop AUC in dermatopathology. Methods The RAND/UCLA appropriateness...

article

Cutaneous Involvement by Nasal Mucoepidermoid Carcinoma: The Tip of the Iceberg Phenomenon

Ge Zhao, Oliver Chang, John Streidl, Amit Bhrany, more

Journal of Cutaneous Pathology > 44 > 2 > 113 - 117

chapter

Special Techniques for the Study of Cutaneous Neural Tumors

Zsolt Argenyi, Chris H. Jokinen

Current Clinical Pathology > Cutaneous Neural Neoplasms > 7-14

A variety of histochemical and immunohistochemical methods, if employed in the appropriate context and in a suitable combination, are useful for identifying and classifying cutaneous neural tumors.

chapter

Benign Cutaneous Neoplasms with Peripheral Nerve Differentiation

Zsolt Argenyi, Chris H. Jokinen

Current Clinical Pathology > Cutaneous Neural Neoplasms > 37-82

Neurofibroma (NF) is one of the most commonly encountered benign peripheral nerve sheath tumors in the skin (Fig.a, b for line drawing). Because NF is composed of each element of the peripheral nerve, it most likely represents a hamartoma. Some authors, however, contend NF is a neoplasm as it is associated with mutation in the neurofibromatosis type 1 (NF1) gene. Furthermore, neurofibroma may undergo...

chapter

Cutaneous Neuroblastic and Ganglion Cell Proliferations

Zsolt Argenyi, Chris H. Jokinen

Current Clinical Pathology > Cutaneous Neural Neoplasms > 113-118

Neuroblastoma is a malignant neoplasm of neural crest lineage, most often arising in the adrenal medulla, paraganglia, or sympathetic chain. Cutaneous neuroblastoma usually represents metastasis from a visceral primary. However, rare cutaneous neuroblastoma may develop de novo without an identifiable visceral tumor, possibly from heterotopic neural crest cells. Neuroblastoma represents the most primitive...

chapter

Malignant Cutaneous Neoplasms with Peripheral Nerve Differentiation

Zsolt Argenyi, Chris H. Jokinen

Current Clinical Pathology > Cutaneous Neural Neoplasms > 83-91

Malignant peripheral nerve sheath tumor (MPNST) of the skin is a rare superficial sarcoma, capable of locally destructive growth and systemic metastasis. By definition, MPNST arises from a preexisting peripheral nerve sheath tumor or a nerve de novo. In the former circumstance, nearly all arise from a neurofibroma with a high association with the plexiform variant. Rare deeper variants of MPNST with...

chapter

The Peripheral Nerve and Cutaneous Neural Tumors: Introduction, Definitions, and Classification

Zsolt Argenyi, Chris H. Jokinen

Current Clinical Pathology > Cutaneous Neural Neoplasms > 1-6

Peripheral nerves, brain, and spinal cord comprise the neural organ system, which is traditionally divided by its components into the peripheral nervous system and central nervous system. Cutaneous peripheral nerves are responsible for the transmission of sensory information, motor function, and control of multiple functions vital to preservation of the integument and survival of the human. Among...

chapter

Cutaneous Proliferations with Putative Neural Differentiation

Zsolt Argenyi, Chris H. Jokinen

Current Clinical Pathology > Cutaneous Neural Neoplasms > 93-111

Neurothekeoma (NTK) is a neoplasm of uncertain lineage. Previous descriptions classified NTK as cellular (immature) and myxoid (mature; classical) types based on the degree of cellularity. Currently, however, it is suggested that some highly myxoid and the previously described transitional or mixed variants with evidence of schwannian differentiation are better classified as dermal nerve sheath myxoma...

chapter

Cutaneous Glial and Meningothelial Proliferations

Zsolt Argenyi, Chris H. Jokinen

Current Clinical Pathology > Cutaneous Neural Neoplasms > 119-126

Glial and meningothelial proliferations of the skin are rare. In this chapter, nasal glioma (glial heterotopia), meningocele, and cutaneous meningioma are discussed. As a group, these lesions represent a spectrum of abnormalities related to abnormal closure of the neural tube or abnormal migration of neural crest cells during development; therefore, semantically some of them are not considered true...

chapter

Nonneoplastic and Hamartomatous Lesions of the Cutaneous Peripheral Nerve

Zsolt Argenyi, Chris H. Jokinen

Current Clinical Pathology > Cutaneous Neural Neoplasms > 15-36

Nonneoplastic neural proliferations are among the most commonly encountered peripheral nerve sheath tumors in the skin. This chapter describes the various hamartomas (neuromas) and reparative or reactive proliferations that develop following nerve injury. In general, hamartomatous lesions of the skin constitute proliferations of each of the normal elements of the peripheral nerve fiber including Schwann...

book

Cutaneous Neural Neoplasms

Zsolt Argenyi, Chris H. Jokinen

Current Clinical Pathology

As a result to the recent significant developments, both in the field of cutaneous pathology and clinical dermatology, many cutaneous neural tumors are now being diagnosed by specialists like dermatopathologists, and treated by dermatologists or dermatologic surgeons. Cutaneous Neural Neoplasms: A Practical Guide provides an essential aid in diagnosis by discussing the cardinal clinico-pathologic...

article

Prior knowledge of the clinical picture does not introduce bias in the histopathologic diagnosis of melanocytic skin lesions

Gerardo Ferrara, Giorgio Annessi, Zsolt Argenyi, Giuseppe Argenziano, more

Journal of Cutaneous Pathology > 42 > 12 > 953 - 958

A common debate among dermatopathologists is that prior knowledge of the clinical picture of melanocytic skin neoplasms may introduce a potential bias in the histopathologic examination. Histologic slides from 99 melanocytic skin neoplasms were circulated among 10 clinical dermatologists, all of them formally trained and board‐certified dermatopathologists: 5 dermatopathologists had clinical images...

article

Diameter of dysplastic nevi is a more robust biomarker of increased melanoma risk than degree of histologic dysplasia: A case-control study

Michael Y. Xiong, Michael S. Rabkin, Michael W. Piepkorn, Raymond L. Barnhill, more

Journal of the American Academy of Dermatology > 2014 > 71 > 6 > 1257-1258.e4

article

Cutaneous epithelioid melanocytic neurofibroma arising in a patient with neurofibromatosis‐1

Roberto A. Novoa, Carrie L. Kovarik, David W. Low, Zsolt Argenyi

Journal of Cutaneous Pathology > 41 > 5 > 457 - 461

Tumors expressing both melanocytic and neural features can pose a diagnostic challenge to the dermatopathologist and provoke questions regarding their lineage. We report a case of a tumor arising on the right cheek of a 9‐year‐old boy with neurofibromatosis type 1 (NF‐1). This neoplasm featured nests of non‐pigmented epithelioid cells arising within a neurofibroma. The entire tumor stained strongly...

article

Cutaneous and mucosal mucormycosis mimicking pancreatic panniculitis and gouty panniculitis

Luis Requena, Panitta Sitthinamsuwan, Carlos Santonja, María Teresa Fernández-Figueras, more

Journal of the American Academy of Dermatology > 2012 > 66 > 6 > 975-984

Histopathologic study of lesions of cutaneous mucormycosis usually shows suppurative granulomas involving the deep dermis and subcutaneous fat. Large, broad and non-septate fungal hyphae are easily identified within the necrotic areas.The main goal of our study is to describe the histopathologic features of 13 cases of cutaneo-mucous mucormycosis, which mimicked the findings of pancreatic and/or gouty...

article

Plexiform melanocytic schwannoma: a mimic of melanoma

Iwei Yeh, Zsolt Argenyi, Swapna S. Vemula, Paul S. Furmanczyk, more

Journal of Cutaneous Pathology > 39 > 5 > 521 - 525

We present a unique dermal tumor for which we propose the term plexiform melanocytic schwanomma. The proliferation consisted of lobules of epithelioid and spindled cells with S100, Melan‐A and HMB‐45 positivity but without obvious melanin pigmentation. The nuclei were moderately pleomorphic in some areas, and in a few areas the mitotic index was elevated. Schwannian differentiation was inferred from...

article

Clinicopathologic features of early lesions of primary cutaneous follicle center lymphoma, diffuse type: Implications for early diagnosis and treatment

Andrea Gulia, Andrea Saggini, Thomas Wiesner, Regina Fink-Puches, more

Journal of the American Academy of Dermatology > 2011 > 65 > 5 > 991-1000.e7

Data on early lesions of primary cutaneous follicle center lymphoma (PCFCL), diffuse type are very limited.We sought to elucidate the early clinicopathologic features of PCFCL, diffuse type.Clinical, histologic, immunohistologic, molecular, and fluorescence in situ hybridization data from 24 patients with early lesions of PCFCL, diffuse type (male:female = 19:5; median age: 57 years) were determined...

article

Influence of evaluation of clinical pictures on the histopathologic diagnosis of inflammatory skin disorders

Lorenzo Cerroni, Zsolt Argenyi, Rino Cerio, Fabio Facchetti, more

Journal of the American Academy of Dermatology > 2010 > 63 > 4 > 647-652

Clinical information on histologic referral sheets is usually very limited, and particularly for inflammatory skin disorders, dermatopathologists often ask referring physicians for clinical correlation.In this study we tested the value of clinicopathologic correlation in the histopathologic diagnosis of inflammatory skin disorders.One-hundred biopsy specimens were digitalized and stored on 3 DVDs...

article

Histopathologic characterization of epidermolytic hyperkeratosis: A systematic review of histology from the National Registry for Ichthyosis and Related Skin Disorders

Rustin Ross, John J. DiGiovanna, Laura Capaldi, Zsolt Argenyi, more

Journal of the American Academy of Dermatology > 2008 > 59 > 1 > 86-90

The clinical condition generalized epidermolytic hyperkeratosis, also known as bullous congenital ichthyosiform erythroderma, is an autosomal dominant disorder and presents as a bullous disease of the newborn followed by an ichthyotic skin disorder throughout life. Clinical epidermolytic hyperkeratosis (cEHK) has characteristic histopathologic findings. Mosaic cEHK, which occurs without a family history,...

article

Histopathologic Diagnosis of Chronic Graft-versus-Host Disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: II. Pathology Working Group Report

Howard M. Shulman, David Kleiner, Stephanie J. Lee, Thomas Morton, more

Biology of Blood and Marrow Transplantation > 2006 > 12 > 1 > 31-47

This consensus document provides an update for pathologists and clinicians about the interpretation of biopsy results and use of this information in the management of hematopoietic cell transplantation patients. Optimal sampling and tissue preparation are discussed. Minimal criteria for the diagnosis of graft-versus-host disease (GVHD) are proposed, together with specific requirements for the diagnosis...

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© 2015 Interdisciplinary Centre for Mathematical and Computational Modelling

Financed by the National Centre for Research and Development under grant No. SP/I/1/77065/10 by the strategic scientific research and experimental development program: SYNAT - “Interdisciplinary System for Interactive Scientific and Scientific-Technical Information”.