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In addition to the transport of food and liquid from the mouth to the stomach by primary peristalsis, another important function of the esophagus is to prevent gastric contents that are refluxed into the esophagus from being aspirated into the airways. This function depends on secondary peristalsis and coordination with the esophageal sphincters, which is stimulated by distention of the body of the...
This review focuses on primary peristalsis and the normal swallow and secondary peristalsis as it relates to esophageal distention. In addition, high-pressure zones in the esophageal sphincters and innervation in the esophageal body are discussed. Distention-induced protective reflexes for the pharynx and airway are described, as are extraesophageal effects of esophageal distention. Experimental and...
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