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Primary cutaneous sarcomas account for 14% of all sarcomas [1]. Partly owing to their relative rarity, diagnosis of these tumors is often challenging. All too often a pathologist is faced with a small biopsy, and has to differentiate a common benign mesenchymal tumor from its malignant counterpart, or classify a malignant tumor based on a limited tissue sample. Fortunately, basic science discoveries...
Programmed cell death (PCD) is utilized in a wide variety of tissues to refine structure in developing tissues and organs. However, little is understood about the mechanisms that, within a developing epithelium, combine signals to selectively remove some cells while sparing essential neighbors. One popular system for studying this question is the developing Drosophila pupal retina, where excess interommatidial...
Behavioral development in the adult worker honey bee (Apis mellifera), from performing tasks inside the hive to foraging, is associated with an increase in the blood titer of juvenile hormone III (JH), and hormone treatment results in precocious foraging. To study behavioral development in the absence of JH we removed its glandular source, the corpora allata, in 1-day-old adult bees. The age at onset...
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