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The base hydrolysis of Malachite green (MG+) was studied in aqueous solution of mixed surfactants of sodium dodecyl sulfate (SDS) and Triton X-100 (TX-100) at 25 °C. The results show that the SDS/TX-100 system compositions has relatively significant influence on the rate constant of the base hydrolysis of MG+ when compared with the reaction in the respective single surfactant systems.