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Previous studies reported higher interleukin-6 (IL-6) levels in systemic lupus erythematosus (SLE) patients than in healthy controls. However, the clinical relevance of IL-6 in SLE has not been clearly established.The present study aimed to evaluate the clinical significance of serum and urinary IL-6 and their usefulness as markers of disease activity in SLE.63 SLE patients were included. Disease...
The question of the mechanism by which the Gram-negative intestinal microflora acts as an antigenic stimulus for the development of immune reactions in the newborn was studied. Using newborn bacteria-free piglets artificially monocontaminated withE coli P-1 as the model, it was determined whether somatic antigens are released and absorbed in the intestine and infiltrate into the organism. The presence...
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