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The mechanism underlying the impairment of the function of the cellular component of the immune response and its regulation by vitamin D3 in diabetes mellitus remains incompletely characterized. The present study addresses the specific features of the functioning of the T-cell link of immune response and the humoral response to injecyion of an artificial antigen in a diabetes model and after prolonged...
Experimental streptozotocin type 1 diabetes in mice is characterized by a significant deficiency of vitamin D 3 , detected by decreased level of serum 25(OH)D 3 . This vitamin D 3 deficiency correlated with impairments of mineral metabolism in bone tissue, indicating the development of secondary osteoporosis. There was a decrease of the mass, length, and...
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