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Study Type – Aetiology (cohort)Level of Evidence 2b
OBJECTIVE• To describe clinical and histopathological characteristics of Finnish familial prostate cancer (PCa) through a detailed analysis of cases in families.
PATIENTS AND METHODS• In total, 202 Finnish families with 617 histopathologically confirmed PCa cases of confirmed genealogy were collected.• Complete clinical data, including age and...
Prostate cancer (PCa) is the most frequently diagnosed cancer in men worldwide and is likely to be caused by a number of genes with different modes of inheritance, population frequencies and penetrance. The objective of this study was to assess the familial aggregation of PCa in a sample of 1,546 nuclear families ascertained through an affected father and diagnosed during 1988–1993, from the unique,...
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