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Die Sepsis bleibt trotz starker Anstrengungen in den letzten Jahren ein Krankheitsbild mit hoher Letalität und steigenden Fallzahlen. Eine frühe Diagnosestellung, konsequente Diagnostik, zeitgerechte Einleitung einer adäquaten antimikrobiellen und supportiven Therapie sowie ggf. eine Fokussanierung sind wichtige Bausteine für einen Therapieerfolg. Die neuen internationalen Sepsis-Leitlinien stellen...
Objectives Early broad-spectrum antimicrobial treatment reduces mortality in patients with septic shock. In a multicenter, prospective observational study, we explored whether delayed appropriate antimicrobial therapy (AAT) influences outcome in Staphylococcus aureus bloodstream infection (SAB). Methods Two hundred and fifty-six patients with SAB from ten German study centers were enrolled and followed...
Yersinia pseudotuberculosis belongs to the family Enterobacteriaceae and is known to cause enterocolitis, terminal ileitis, pseudoappendicitis, erythema nodosum, reactive polyarthritis, and, occasionally, bloodstream infections. Here, we report the first case of bacteremia and septic arthritis in a patient without obvious risk factors and review all of the published cases of Y. pseudotuberculosis...
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