Search results for: Masae Fujii

Items from 1 to 3 out of 3 results

article

Parenchyma–stromal interactions induce fibrosis by secreting CCN2 and promote osteoclastogenesis by stimulating RANKL and CD68 through activated TGF‐β/BMP4 in ameloblastoma

Yuichiro Takebe, Hidetsugu Tsujigiwa, Naoki Katase, Chong Huat Siar, more

Journal of Oral Pathology & Medicine > 46 > 1 > 67 - 75

Background Tumor parenchyma–stromal interactions affect the properties of tumors and their dynamics. Our group previously showed that secreted frizzled related protein (sFRP)‐2 impairs bone formation and promotes bone invasion in ameloblastoma. However, the effects of the secreted growth factors CCN2, TGF‐β, and BMP4 on stromal tissues in ameloblastoma remain unclear. Materials and results Thirty‐five...

article

Dickkopf (Dkk)-3 and β-catenin expressions increased in the transition from normal oral mucosal to oral squamous cell carcinoma

Masae Fujii, Naoki Katase, Mathieu Lefeuvre, Mehmet Gunduz, more

Journal of Molecular Histology > 2011 > 42 > 6 > 499-504

Dickkopf (Dkk)-3, an inhibitor of the Wnt/β-catenin pathway, is reported as a potential tumor suppressor gene in many cancers. To gain a better comprehension of the mechanisms involved in the carcinogenesis of oral squamous epithelium, protein expression and localization of Dkk-3 and β-catenin was investigated in normal epithelium, dysplasias and squamous cell carcinoma (SCC). An increase in β-catenin...

article

Dynamic contrast-enhanced magnetic resonance imaging for estimating tumor proliferation and microvessel density of oral squamous cell carcinomas

Teruhisa Unetsubo, Hironobu Konouchi, Yoshinobu Yanagi, Jun Murakami, more

Oral Oncology > 2009 > 45 > 7 > 621-626

We evaluated the relationship between histopathological prognostic factors, tumor proliferation microvessel density (MVD), and enhancement parameters in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in oral squamous cell carcinoma (SCC). Twenty-eight T2 and T3 patients with primary oral SCC underwent DCE-MRI using three-dimensional fast imaging with a steady-state precession sequence...

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Search results for: Masae Fujii

Parenchyma–stromal interactions induce fibrosis by secreting CCN2 and promote osteoclastogenesis by stimulating RANKL and CD68 through activated TGF‐β/BMP4 in ameloblastoma

Dickkopf (Dkk)-3 and β-catenin expressions increased in the transition from normal oral mucosal to oral squamous cell carcinoma

Dynamic contrast-enhanced magnetic resonance imaging for estimating tumor proliferation and microvessel density of oral squamous cell carcinomas

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