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The prepuce is apparent prenatally at 8 weeks of gestation as a ridge of thickened epithelium. The prepuce grows forward over the glans to completion by 16 weeks of gestation. Early in gestation there is no separation between the epithelium lining the prepuce and glans. Preputial adhesions are a characteristic of normal development with initiation of spontaneous separation by desquamation late in...
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