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Cell population enriched by determined cells, the precursors of dopaminergic neurons can be used for neurotransplantation. In order to obtain such cell population, we studied the potentialities of dopaminergic differentiation of human embryonic nervous tissue in a cell culture. A number of dopaminergic neurons during cultivation significantly increased from 5.6 ± 4.3% of cells within eyeshot to 23...
We studied the mitogenic and differentiation potential and the remyelination properties of human embryonic nerve cells in culture. After 1 month of cultivation without differentiation agents, a 3.6-fold increase in the number of CNP-positive cells (the mitotically active precursors of oligodendrocytes) was observed. At the same time, the number of GalC-positive cells (mature oligodendrocytes) remained...