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The insulin-like growth factor (IGF) system plays essential role in the regulation of cell growth, proliferation and survival and affects nearly every organ system in the body. IGF-I, which has a high structural similarity to insulin, exerts growth-promoting effects, influences glucose metabolism and has neuroprotective and cardioprotective effects, partly because of its cell-proliferative and antiapoptotic...
To determine the effect of the GHRH antagonist JV-1-36 on proliferation and survival of primary ectopic human endometriotic stromal cells (ESCs) and the T HESC cell line.Prospective laboratory study.University hospital.22 women with endometriosis (aged 34.8 ± 5.7 years) undergoing therapeutic laparoscopy.Eutopic (n=10) and ectopic (n=22) endometrial tissues were collected from women who underwent...
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