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Summary. There is good empirical evidence that specific flaws in the conduct of randomized controlled trials are associated with exaggeration of treatment effect estimates. Mixed treatment comparison meta‐analysis, which combines data from trials on several treatments that form a network of comparisons, has the potential both to estimate bias parameters within the synthesis and to produce bias‐adjusted...
AIM: o present the evidence summarized in the Cochrane fluoride reviews. STUDY DESIGN: An overview of the results of selected systematic reviews. METHODS: Relevant systematic reviews published in the Cochrane Database of Systematic Reviews (CDSR) were identified by searching ‘The Cochrane Library issue 4, 2008’, using the terms ‘Fluoride’ and ‘Caries’. Complete Cochrane reviews assessing the effectiveness...
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