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Dietary oligosaccharides can influence the composition of the gut microbiota, and some are suggested to improve host resistance against infections. The exact mechanisms involved are largely unknown. The aim of the present study was to determine the response of the porcine small intestinal mucosa to feeding arabinoxylan oligosaccharides (AXOS), and whether it modulated the response to a single bacterial...
The high similarity between pigs and humans makes pigs a good gastrointestinal (GI) model for humans. Recently an epithelial cell line originating from the jejunum of pig (IPEC-J2) became available. Once validated, this model can be used to investigate the complex interactions occurring in the intestine. The advantages of using IPEC-J2 as in vitro model of the GI tract are the high resemblance between...
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