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Magnetic nanoparticle (MNP) thermometry will be necessary for safe therapeutic implementation of magnetic nanoparticle hyperthermia, a developing cancer treatment. One realization of a MNP thermometer works by detecting harmonic signal (the fundamental f and 3f harmonics) generated by MNPs exposed to ac magnetic field. In this paper, we aim to measure accurately the harmonic signal in a MNP thermometer,...
This article aims to the problems that the particle swarm optimization (PSO) algorithm has slow convergence and easy to fall into local optimum, provides an improved adaptive particle swarm optimization algorithm based on Levy flight mechanism (LFAPSO). The long jumps of Levy flight will step out of the local optimum in the local search. The convergence speed and accuracy of the LFAPSO algorithm are...
This paper reports on a new system of magnetic nanoparticle spectrometer to measure the magnetization spectrum of a magnetic nanoparticle based sample induced in alternating magnetic field with low frequency ( f = 192 Hz) for noninvasive magnetic nanothermometry. The achieved magnetic nanothermometer employs the measured fundamental and third harmonics in ac magnetic field (fundamental and second...
In recent years, a thermotherapy based on magnetic fluid nanomaterials can be used not only to generate heat, but also to deliver and release drugs in the process of treatment, even if the tissue tumors is deep [1]. Hence, the unique approach of magnetic fluid nanomaterials hyperthermia is becoming a promising treatment. However, the spread of nanomaterials to normal tissues around the tumor is inevitable...
Magnetic nanoparticle temperature estimation by AC magnetization spectrum is a novel, precise and noninvasive temperature measurement approach[1-5]. Fluctuation of AC applied magnetic field is one of important impact factors that leading to temperature error. This study aims to evaluate the impact of the fluctuation of AC applied magnetic field upon the accuracy of the temperature estimation while...
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