Search results for: Xiaolu Zhu

Items from 1 to 20 out of 46 results

article

COVID‐19 infection in patients with haematological malignancies: A single‐centre survey in the latest Omicron wave in China

Xiaolu Zhu, Qian Jiang, Jin Lu, Yuqian Sun, more

British Journal of Haematology > 202 > 1 > 31 - 39

As the COVID‐19 variant Omicron surge in Beijing, China, a better understanding of risk factors for adverse outcomes may improve clinical management in patients with haematological malignancies (HM) diagnosed with COVID‐19. The study sample includes 412 cases, mainly represented by acute leukaemia, chronic myeloid leukaemia (CML), plasma cell disorders and lymphoma and chronic lymphocytic leukaemia...

article

The application of plan, do, check, act (PDCA) quality management in reducing nosocomial infections in endoscopy rooms: It does work

Xiaoming Kong, Xiaolu Zhu, Yidan Zhang, Jie Wu

International Journal of Clinical Practice > 75 > 8 > n/a - n/a

Background The role of plan, do, check, act (PDCA) cycle quality management in reducing nosocomial infections in endoscopy rooms remains unclear; we aimed to evaluate the effects of PDCA in the nosocomial infections control of endoscopy rooms. Methods This present study was a before and after design. The patients treated in our endoscopy room from 1 January 2019 to 31 December 2019 were included...

article

The regulatory function of tandem repeat VNTR2‐1 in hTERT gene involves basic Helix–loop–helix family transcription factors

Xiaolu Zhu, Tao Xu, Jiyue Zhu

Environmental and Molecular Mutagenesis > 62 > 6 > 338 - 349

Telomerase is a ribonucleoprotein enzyme that synthesizes telomere end sequence. The expression of hTERT gene, encoding the catalytic subunit of human telomerase, is restricted to highly proliferative tissues and is undetectable in most somatic cells. Abnormal activation of hTERT gene is found in 90% of human tumors. Previously, we identified tandem repeat of 42‐bp/unit, VNTR2‐1, in intron 2 of the...

article

Facile preparation of Ag/Ag₂WO₄/g‐C₃N₄ ternary plasmonic photocatalyst and its visible‐light photocatalytic activity

Jiang Li, Xiaolu Zhu, Fengxian Qiu, Tao Zhang, more

Applied Organometallic Chemistry > 33 > 3 > n/a - n/a

Introducing plasmonic metals into semiconductor materials has been proven to be an attractive strategy for enhancing photocatalytic activity in the visible region. In this work, a novel and efficient Ag/Ag₂WO₄/g‐C₃N₄ (AACN) ternary plasmonic photocatalyst was successfully synthesized using a facile one‐step in situ hydrothermal method. The composition, structure, morphology and optical absorption...

article

Study on Random Fracture and Crack Growth of Gear Tooth Waist

Xinxiao Bian, Xiaole Li, Xiaolu Zhu

Journal of Failure Analysis and Prevention > 2018 > 18 > 1 > 121-129

The gear tooth fracture usually occurs at the root, but sometimes also occurs at the waist, or even at the top. The random fracture is defined as the rupture at the waist or top of the tooth. The random fracture at the waist is studied in this paper. In order to simulate a manufacturing defect on the tooth surface, a mic-notch (a minute notch) was cut at the waist of the twelve teeth in the two test...

article

The antiepileptic drug levetiracetam promotes neuroblast differentiation and expression of superoxide dismutase in the mouse hippocampal dentate gyrus via PI3K/Akt signalling

Bing Chun Yan, Hui Shen, Yuanyuan Zhang, Xiaolu Zhu, more

Neuroscience Letters > 2018 > 662 > C > 84-90

Levetiracetam (LEV), a second-generation antiepileptic drug, is commonly prescribed to treat certain types of seizures. Few studies have investigated the effects of LEV on hippocampal neurogenesis and its related mechanisms. In the present study, we investigated the effects of LEV on cell proliferation and neuronal differentiation in the mouse hippocampal dentate gyrus (DG). We here demonstrate a...

article

Diminished expression of β2-GPI is associated with a reduced ability to mitigate complement activation in anti-GPIIb/IIIa-mediated immune thrombocytopenia

Xiaolu Zhu, Jiamin Zhang, Qianming Wang, Haixia Fu, more

Annals of Hematology > 2018 > 97 > 4 > 641-654

Anti-GPIIb/IIIa-mediated complement activation has been reported to be important in the pathogenesis of immune thrombocytopenia (ITP). However, the role of the complement system and the involved regulatory mechanism remain equivocal. Beta2-glycoprotein I (β2-GPI), known as the main target for antiphospholipid autoantibodies, has been demonstrated as a complement regulator. Here, we investigated the...

article

Both decreased Akt expression and mTOR phosphorylation are related to decreased neuronal differentiation in the hippocampal alveus of aged mice

Bing Chun Yan, Dan Jiang, Jie Wang, Yuanyuan Zhang, more

Aging Clinical and Experimental Research > 2018 > 30 > 7 > 737-743

Background Aging is an inevitable process which results in many changes. These changes are closely related to the hippocampus which is in charge of long-term learning and episodic memory. Aim This study was to investigate age-related changes of the cell proliferation, neuroblast differentiation and Akt/mTOR signaling in the hippocampal alveus of aged mice. Methods In the present study, we compared...

chapter

Theoretically Evaluating the Electric Property of Electric Double Layer at Electrode/Electrolyte Interfaces with Heterogeneous Dielectric Properties

Xiaolu Zhu, Changzhen Jiang

2017 International Conference on Sensing, Diagnostics, Prognostics, and Control (SDPC) > 504 - 509

2017 International Conference on Sensing, Diagnostics, Prognostics, and Control (SDPC)

Electric double layers (EDL) with different dielectric constants in the condensed layer, outer diffuse layer and bulk solution were theoretically studied by considering the steric effect of ions with the EDL. The expressions of condensed layer thickness, total charge and capacitance of the EDL are derived, and their variation with the bulk ion concentration, applied voltage and the dielectric constant...

article

Fabrication of a novel hierarchical flower-like hollow structure Ag2WO4/WO3 photocatalyst and its enhanced visible-light photocatalytic activity

Fengxian Qiu, Xiaolu Zhu, Qing Guo, Yuting Dai, more

Powder Technology > 2017 > 317 > C > 287-292

A series of hierarchical flower-like hollow structure Ag₂WO₄/WO₃ photocatalysts was synthesized and characterized by XRD, SEM, Raman spectroscopy, XPS, photoluminescence (PL) spectra, and BET. The obtained results indicated the growth of finely distribution of Ag₂WO₄ on the surface of the WO₃ hollow sphere. UV–vis diffuse reflectance spectroscopy (DRS) was used to investigate the absorption range...

chapter

Hollow spheroid formation by cells at the mechanical interface of hyaluronic acid hydrogels in three dimensions

Xiaolu Zhu, Yifei Yang

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) > 218 - 222

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)

Extracellular matrix (ECM) is a non-cellular material that offers not only structural/mechanical support but also chemical and physical guidance cues for cells. Cellular self-organization is highly related to the property of ECM. Here, we investigate the 3D hollow spheroid formation process of vascular mesenchymal cells (VMCs) at the interfaces between hydrogel ECMs with different mechanical properties...

chapter

Learning Transportation Mode Choice for Context-Aware Services with Directed-Graph-Guided Fused Lasso from GPS Trajectory Data

Xiaolu Zhu, Jinglin Li, Zhihan Liu, Fangchun Yang

2017 IEEE International Conference on Web Services (ICWS) > 692 - 699

2017 IEEE International Conference on Web Services (ICWS)

Mobility profiles of users play a crucial role in a wide range of context-aware computing and services. Travel mode choice, as a representative feature of mobility profiles, is one of the important components in travel demand and future planning of transportation systems. Transportation mode choice has been widely studied based on the random utility model and decision making methods which haven't...

article

Directing three-dimensional multicellular morphogenesis by self-organization of vascular mesenchymal cells in hyaluronic acid hydrogels

Xiaolu Zhu, Shiva Gojgini, Ting-Hsuan Chen, Peng Fei, more

Journal of Biological Engineering > 2017 > 11 > 1 > 1-12

Background Physical scaffolds are useful for supporting cells to form three-dimensional (3D) tissue. However, it is non-trivial to develop a scheme that can robustly guide cells to self-organize into a tissue with the desired 3D spatial structures. To achieve this goal, the rational regulation of cellular self-organization in 3D extracellular matrix (ECM) such as hydrogel is needed. Results In this...

chapter

A Joint Grid Segmentation Based Affinity Propagation Clustering Method for Big Data

Xiaolu Zhu, Jinglin Li, Zhihan Liu, Fangchun Yang

2016 IEEE 18th International Conference on High Performance Computing and Communications; IEEE 14th International Conference on Smart City; IEEE 2nd International Conference on Data Science and Systems (HPCC/SmartCity/DSS) > 1232 - 1233

Clustering is useful for discovering underlying groups and identifying interesting patterns in scientific data and engineering systems. Affinity propagation (AP) is an effective clustering algorithm which has been successfully applied to broad areas of computer science. To generate high quality clusters, AP iteratively performs information propagation on the full similarity matrix and requires excessive...

article

Facile preparation of glucose functionalized multi-wall carbon nanotubes and its application for the removal of cationic pollutants

Jian Rong, Xinshan Rong, Fengxian Qiu, Xiaolu Zhu, more

Materials Letters > 2016 > 183 > C > 9-13

Glucose functionalized multi-wall carbon nanotubes (MWCNT/Gl) composites adsorbent was prepared. Adsorption characteristic of MWCNT/Gl was applied to deal with wastewater solution containing rhodamine B (RhB), methylene blue (MB), methyl orange (MO), malachite green (MG) and congo red (CR). The effects of adsorbent dosage, dye species, pH and contact time were conducted, and the adsorption kinetic...

article

Preparation of hierarchical micro/nanostructured Bi2S3-WO3 composites for enhanced photocatalytic performance

Jian Rong, Tao Zhang, Fengxian Qiu, Xinshang Rong, more

Journal of Alloys and Compounds > 2016 > 685 > C > 812-819

Novel hierarchical micro/nanostructured photocatalysts composed of WO₃ microspheres and needle-like Bi₂S₃ nanocrystals were successfully synthesized by a simple combination of hydrothermal and post-calcination method. The as-obtained Bi₂S₃-WO₃ composites was applied for photocatalytic removal of Rhedamine B (RhB) organic pollution in water under visible light irradiation. The morphology and structure...

article

Thermal behavior and kinetic study for catalytic co-pyrolysis of biomass with plastics

Xuesong Zhang, Hanwu Lei, Lei Zhu, Xiaolu Zhu, more

Bioresource Technology > 2016 > 220 > C > 233-238

The present study aims to investigate the thermal decomposition behaviors and kinetics of biomass (cellulose/Douglas fir sawdust) and plastics (LDPE) in a non-catalytic and catalytic co-pyrolysis over ZSM-5 catalyst by using a thermogravimetric analyzer (TGA). It was found that there was a positive synergistic interaction between biomass and plastics according to the difference of weight loss (ΔW),...

article

Topiramate Improves Neuroblast Differentiation of Hippocampal Dentate Gyrus in the d-Galactose-Induced Aging Mice via Its Antioxidant Effects

Hui Shen, Jie Wang, Dan Jiang, Pei Xu, more

Cellular and Molecular Neurobiology > 2017 > 37 > 5 > 869-877

Some anticonvulsant drugs are associated with cognitive ability in patients; Topiramate (TPM) is well known as an effective anticonvulsant agent applied in clinical settings. However, the effect of TPM on the cognitive function is rarely studied. In this study, we aimed to observe the effects of TPM on cell proliferation and neuronal differentiation in the dentate gyrus (DG) of the d-galactose-induced...

article

Individualizing drug dosage with longitudinal data

Xiaolu Zhu, Annie Qu

Statistics in Medicine > 35 > 24 > 4474 - 4488

We propose a two‐step procedure to personalize drug dosage over time under the framework of a log‐linear mixed‐effect model. We model patients' heterogeneity using subject‐specific random effects, which are treated as the realizations of an unspecified stochastic process. We extend the conditional quadratic inference function to estimate both fixed‐effect coefficients and individual random effects...

chapter

Simulation for tubular and spherical structure formation via self- organization of vascular mesenchymal cells in three dimensions

Xiaolu Zhu, Yifei Yang

2016 9th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI) > 1654 - 1659

2016 9th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI)

Cellular self-organization in extracellular matrix (ECM) is a complex process highly related to ECM proteins, cytokines, growth factors, cell-cell contacts, and mechanical stimuli, and study on the underlying mechanism is vital for rationally tuning the self-organization of cells. Here, we investigate the 3D pattern formation process of vascular mesenchymal cells (VMCs) at the interfaces between hydrogels...

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INFONA - science communication portal

Search results for: Xiaolu Zhu

COVID‐19 infection in patients with haematological malignancies: A single‐centre survey in the latest Omicron wave in China

The application of plan, do, check, act (PDCA) quality management in reducing nosocomial infections in endoscopy rooms: It does work

The regulatory function of tandem repeat VNTR2‐1 in hTERT gene involves basic Helix–loop–helix family transcription factors

Facile preparation of Ag/Ag₂WO₄/g‐C₃N₄ ternary plasmonic photocatalyst and its visible‐light photocatalytic activity

Study on Random Fracture and Crack Growth of Gear Tooth Waist

The antiepileptic drug levetiracetam promotes neuroblast differentiation and expression of superoxide dismutase in the mouse hippocampal dentate gyrus via PI3K/Akt signalling

Diminished expression of β2-GPI is associated with a reduced ability to mitigate complement activation in anti-GPIIb/IIIa-mediated immune thrombocytopenia

Both decreased Akt expression and mTOR phosphorylation are related to decreased neuronal differentiation in the hippocampal alveus of aged mice

Theoretically Evaluating the Electric Property of Electric Double Layer at Electrode/Electrolyte Interfaces with Heterogeneous Dielectric Properties

Fabrication of a novel hierarchical flower-like hollow structure Ag2WO4/WO3 photocatalyst and its enhanced visible-light photocatalytic activity

Hollow spheroid formation by cells at the mechanical interface of hyaluronic acid hydrogels in three dimensions

Learning Transportation Mode Choice for Context-Aware Services with Directed-Graph-Guided Fused Lasso from GPS Trajectory Data

Directing three-dimensional multicellular morphogenesis by self-organization of vascular mesenchymal cells in hyaluronic acid hydrogels

A Joint Grid Segmentation Based Affinity Propagation Clustering Method for Big Data

Facile preparation of glucose functionalized multi-wall carbon nanotubes and its application for the removal of cationic pollutants

Preparation of hierarchical micro/nanostructured Bi2S3-WO3 composites for enhanced photocatalytic performance

Thermal behavior and kinetic study for catalytic co-pyrolysis of biomass with plastics

Topiramate Improves Neuroblast Differentiation of Hippocampal Dentate Gyrus in the d-Galactose-Induced Aging Mice via Its Antioxidant Effects

Individualizing drug dosage with longitudinal data

Simulation for tubular and spherical structure formation via self- organization of vascular mesenchymal cells in three dimensions

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