Search results for: Hao Ji

Items from 1 to 20 out of 118 results

article

Increased expression of CEP72 predicts poor prognosis in multiple myeloma

Dan Guo, Jinfeng Lu, Hao Ji, Zenghua Lin, more

International Journal of Laboratory Hematology > 45 > 3 > 317 - 327

Introduction Multiple myeloma (MM) is a fatal hematological malignancy and does not have adequate prognostic indicators. Previous studies indicate that CEP72 is closely related to tumorigenesis and tumor progression. However, the expression and function of CEP72 in multiple myeloma have yet to be elucidated. Methods In this study, we explored the correlation between CEP72 expression and clinicopathological...

article

A Novel InSe‐FET Biosensor based on Carrier‐Scattering Regulation Derived from the DNA Probe Assembly‐Determined Electrostatic Potential Distribution

Hao Ji, Zhenhua Wang, Shun Wang, Chao Wang, more

Advanced Functional Materials > 33 > 14 > n/a - n/a

Low‐dimensional material field‐effect transistor (FET)‐based biosensors have the advantages of high sensitivity, high detection speed, small size, low cost, and excellent compatibility with integrated circuits. The sensing mechanism is extremely important in the design and fabrication of high‐performance FET biosensors in practical applications. Herein, an InSe‐FET biosensor is designed and its dominant...

article

Low COVID‐19 vaccine coverage and guardian acceptance among pediatric transplant recipients

Zhigang Zheng, Yefeng Lu, Min Wang, Yi Luo, more

Journal of Medical Virology > 95 > 1 > n/a - n/a

To investigate COVID‐19 vaccine coverage in immunosuppressed children, assess guardians' intention to vaccinate children, and determine reasons and associated factors. In addition, we attempted to capture the characteristics of them with Omicron. We obtained the vaccination coverage and guardian vaccine acceptance among pediatric transplant recipients through a web‐based questionnaire conducted from...

article

Development and properties of UV‐cured poly (propylene fumarate)/hydroxyapatite composites coatings as potential application for bone adhesive tape

Liang Wang, Bing‐yu Chen, Meng‐hao Ji, Da‐gang Guo, more

Journal of Applied Polymer Science > 139 > 23 > n/a - n/a

As an alternative for polymethyl methacrylate, poly (propylene fumarate) (PPF) has been considered as injectable and biodegradable bone cement; therefore, its mechanical and degradation properties are particularly important. As an environmentally friendly PPF‐based copolymer, which is reinforced by hydroxyapatite, was studied for the properties of the composite. The composites were investigated by...

article

Enhanced oral bioavailability and anti‐hyperuricemic activity of liquiritin via a self‐nanoemulsifying drug delivery system

Chunmei Wei, Qilong Wang, Wen Weng, Michael Adu‐Frimpong, more

Journal of the Science of Food and Agriculture > 102 > 5 > 2032 - 2040

BACKGROUND This study focused on the development of a self‐nanoemulsifying drug delivery system (SNEDDS) to improve, potentially, the solubility and oral bioavailability of liquiritin (LQ). METHODS The solubility of LQ in different types of excipient, namely oils (OLs), emulsifiers (EMs), and co‐emulsifiers (CO‐EMs), was evaluated, and a pseudo‐ternary phase diagram (PTPD) and the formulation optimization...

article

Characterization of a sigma class GST (GSTS6) required for cellular detoxification and embryogenesis in Tribolium castaneum

Xiao‐Wen Song, Qi‐Sheng Zhong, Yan‐Hao Ji, Yue‐Mei Zhang, more

Insect Science > 29 > 1 > 215 - 229

The sigma glutathione S‐transferases (GSTSs) are a class of cytosolic glutathione S transferases (GSTs) that play important roles in antioxidant defense in insects, but the mechanisms by which GSTSs contribute to antioxidant activity remain unclear. Here, we isolated a GSTS (GSTS6) from Tribolium castaneum and explored its function. Homology and phylogenetic analysis revealed that TcGSTS6 shared high...

article

Engineered exosomes for co‐delivery of PGM5‐AS1 and oxaliplatin to reverse drug resistance in colon cancer

Bingqing Hui, Chen Lu, Jing Wang, Yetao Xu, more

Journal of Cellular Physiology > 237 > 1 > 911 - 933

Oxaliplatin resistance inevitably occurs in almost all cases of metastatic colorectal cancer (CRC), and it is important to study the roles of lncRNAs and their specific regulatory mechanisms in oxaliplatin resistance. Exosomes are increasingly designed for drug or functional nucleic acid delivery due to their properties, thereby improving the effectiveness of cancer therapy. The results of this study...

article

Preparation, characterization, pharmacokinetics, and antirenal injury activity studies of Licochalcone A‐loaded liposomes

Jing Liu, Zhongan Zhu, Yuhang Yang, Michael Adu‐Frimpong, more

Journal of Food Biochemistry > 46 > 1 > n/a - n/a

A liposome of Licochalcone A (LCA‐Liposomes) was purposively prepared to ameliorate the low in vivo availability and efficacy of LCA. Physical characterization of LCA‐Liposomes was carried out mainly by determining particle size, morphology, zeta potential (Z‐potential), and efficiency of LCA encapsulation (EE) via appropriate techniques. Also, the rate of LCA release in vitro and distribution in...

article

A novel flame‐retardant electrolyte additive for safer lithium‐ion batteries

Peng Yan, Yucheng Zhu, Xuhai Pan, Hao Ji

International Journal of Energy Research > 45 > 2 > 2776 - 2784

Lithium‐ion batteries (LIBs) have attracted much attention in the field of new energy. However, due to the flammability of its electrolyte, the batteries may have fire or even explosion accidents in unconventional environment. We have synthesized a new electrolyte additive, 1‐diphenylphosphoryloxy‐4‐methylbenzene (DPMB), in the hope of improving the safety performance of LIBs by combining flame‐retardant...

article

State of health prediction model based on internal resistance

Hao Ji, Wei Zhang, Xu‐Hai Pan, Min Hua, more

International Journal of Energy Research > 44 > 8 > 6502 - 6510

The state of health (SOH) is a crucial indicator of lithium‐ion batteries. A battery cycle and calendar life are critical for electric vehicle batteries. Complex interactions occur between the SOH and internal resistance of a battery. In this study, several ternary lithium‐ion battery charge discharge experiments were performed to investigate the effects of the ambient temperature, discharge rate,...

article

Engineering a Nanoscale Al‐MOF‐Armored Antigen Carried by a “Trojan Horse”‐Like Platform for Oral Vaccination to Induce Potent and Long‐Lasting Immunity

Yang‐Bao Miao, Wen‐Yu Pan, Kuan‐Hung Chen, Hao‐Ji Wei, more

Advanced Functional Materials > 29 > 43 > n/a - n/a

Vaccination via the oral administration of an antigen faces many challenges, including gastrointestinal (GI) proteolysis and mucosal barriers. To limit GI proteolysis, a biomimetically mineralized aluminum‐based metal–organic framework (Al‐MOF) system that is resistant to ambient temperature and pH and can act synergistically as a delivery vehicle and an adjuvant is synthesized over a model antigen...

article

CAGW and TAT‐NLS peptides functionalized multitargeting gene delivery system with high transfection efficiency

Xinghong Duo, Lingchuang Bai, Jun Wang, Hao Ji, more

Polymers for Advanced Technologies > 30 > 10 > 2567 - 2576

Gene therapy has attracted much attention in vascular tissue engineering. However, it is still challenging to develop a novel gene carrier with multifunction to overcome the barriers in gene delivery. Herein, the multitargeting gene complexes were developed based on methoxy‐poly(ethylene glycol)‐b‐poly‐(D,L‐lactide‐co‐glycolide) (mPEG‐b‐PLGA), poly(d,l‐lactide‐co‐glycolide)‐g‐polyethylenimine‐g‐CAGW...

article

Self-Micro-Emulsifying Controlled Release of Eugenol Pellets: Preparation, In vitro/In vivo Investigation in Beagle Dogs

Qilong Wang, Min Guo, Michael Adu-Frimpong, Kangyi Zhang, more

AAPS PharmSciTech > 2019 > 20 > 7 > 1-11

This report aimed to formulate self-micro-emulsifying (SMEDDS) controlled-release pellets delivery system to improve aqueous solubility and in vivo availability of eugenol, a main constituent of clove oil with multiple pharmacological activities. The optimal formulation of eugenol-SMEDDS was eugenol: ethyl oleate: cremophor EL: 1, 2-propylene glycol at the ratio of 5:5:12:8. The SMEDDS were observed...

article

Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System

Kangyi Zhang, Qilong Wang, Qiuxuan Yang, Qiuyu Wei, more

AAPS PharmSciTech > 2019 > 20 > 5 > 1-11

The aim of this study was to develop a self-microemulsifying drug delivery system (SMEDDS) for enhancement of the oral bioavailability of isoliquiritigenin (ISL) as well as evaluate its in vivo anti-hyperuricemic effect in rats. The ISL-loaded self-microemulsifying drug delivery system (ISL-SMEDDS) was comprised of ethyl oleate (EO, oil phase), Tween 80 (surfactant), and PEG 400 (co-surfactant). The...

article

Comparative transcriptomic analysis reveals genetic divergence and domestication genes in Diospyros

Changfei Guan, Shuyuan Liu, Mengke Wang, Hao Ji, more

BMC Plant Biology > 2019 > 19 > 1 > 1-14

Background Persimmon (Diospyros kaki) is the most economically cultivated species belonging to the genus Diospyros. However, little is known about the interspecific diversity and mechanism of domestication, partly due to the lack of genomic information that is available for closely related species of D. kaki (DK). Here, we performed transcriptome sequencing on nine samples, including DK, a variety...

article

Effects of Al and Y Addition on Microstructures and Mechanical Properties of As‐Cast Mg–14Li Based Alloy

Zhankui Gao, Wencai Liu, Guohua Wu, Liang Zhang, more

Advanced Engineering Materials > 21 > 2 > n/a - n/a

In this study, effects of Al and Y contents on microstructural evolutions and mechanical properties of the as‐cast Mg–14Li alloy are investigated. The results show that Mg–14Li–xAl (x = 1, 2, 3 wt%) alloys are characterized by predominantly single β–Li and MgLiAl₂ phases. Slight refinement of β–Li grains is obtained with the increasing of Al content. The increased Al addition greatly improves the...

article

Improvement of Charge Injection by Using Separated SiN as Charge Trapping Layer in MONOS Charge Trap Flash Memory

Hao Ji, Yehui Wei, Pengfei Ma, Ran Jiang

IEEE Journal of the Electron Devices Society > 2018 > 6 > 1 > 81 - 84

The charge trapping characteristics in the metal-oxide-nitride-oxide-silicon memory with separated trapping layer were investigated. Charge injection was enhanced for the reduction of effective oxide thickness of the gate dielectric. High program/erase speed as well as large shift of the threshold voltage were obtained. Charges injection was improved according to the constant current stress measurement...

article

Portfolio Diversification Strategy Via Tail‐Dependence Clustering and ARMA‐GARCH Vine Copula Approach

Hao Ji, Hao Wang, Brunero Liseo

Australian Economic Papers > 57 > 3 > 265 - 283

This study proposes a diversified portfolio construction method based on the tail dependence between the financial assets and adopting both market prior information and the exports’ subject views. In this paper, tail‐dependence clustering was applied to divide candidate assets into different groups according to their tail dependence during the crisis period and the ARMA‐GARCH vine copula‐opinion pooling...

article

GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

Ming-Jin Zhang, Wen-Zhi Ren, Xue-Juan Sun, Yang Liu, more

BMC Infectious Diseases > 2018 > 18 > 1 > 1-8

Background With the widespread use of rifampicin and isoniazid, bacterial resistance has become a growing problem. Additionally, the lack of relevant baseline information for the frequency of drug-resistant tuberculosis (TB) gene mutations is a critical issue, and the incidence of this infection in the city of Changchun has not investigated to date. However, compared with the slow traditional methods...

article

Chlorine resistant TFN nanofiltration membrane incorporated with octadecylamine-grafted GO and fluorine-containing monomer

Shuang-Mei Xue, Chen-Hao Ji, Zhen-Liang Xu, Yong-Jian Tang, more

Journal of Membrane Science > 2018 > 545 > C > 185-195

This work describes a novel nanofiltration membrane fabrication strategy in which the octadecylamine-grafted GO with the organophilic property is incorporated in organic phase during interfacial polymerization (IP) in order to protect the polyamide backbone from the attack of free chlorine. Meanwhile, the aqueous phase containing mixed amines of piperazine (PIP) and the fluorine-containing monomer...

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INFONA - science communication portal

Search results for: Hao Ji

Increased expression of CEP72 predicts poor prognosis in multiple myeloma

A Novel InSe‐FET Biosensor based on Carrier‐Scattering Regulation Derived from the DNA Probe Assembly‐Determined Electrostatic Potential Distribution

Low COVID‐19 vaccine coverage and guardian acceptance among pediatric transplant recipients

Development and properties of UV‐cured poly (propylene fumarate)/hydroxyapatite composites coatings as potential application for bone adhesive tape

Enhanced oral bioavailability and anti‐hyperuricemic activity of liquiritin via a self‐nanoemulsifying drug delivery system

Characterization of a sigma class GST (GSTS6) required for cellular detoxification and embryogenesis in Tribolium castaneum

Engineered exosomes for co‐delivery of PGM5‐AS1 and oxaliplatin to reverse drug resistance in colon cancer

Preparation, characterization, pharmacokinetics, and antirenal injury activity studies of Licochalcone A‐loaded liposomes

A novel flame‐retardant electrolyte additive for safer lithium‐ion batteries

State of health prediction model based on internal resistance

Engineering a Nanoscale Al‐MOF‐Armored Antigen Carried by a “Trojan Horse”‐Like Platform for Oral Vaccination to Induce Potent and Long‐Lasting Immunity

CAGW and TAT‐NLS peptides functionalized multitargeting gene delivery system with high transfection efficiency

Self-Micro-Emulsifying Controlled Release of Eugenol Pellets: Preparation, In vitro/In vivo Investigation in Beagle Dogs

Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System

Comparative transcriptomic analysis reveals genetic divergence and domestication genes in Diospyros

Effects of Al and Y Addition on Microstructures and Mechanical Properties of As‐Cast Mg–14Li Based Alloy

Improvement of Charge Injection by Using Separated SiN as Charge Trapping Layer in MONOS Charge Trap Flash Memory

Portfolio Diversification Strategy Via Tail‐Dependence Clustering and ARMA‐GARCH Vine Copula Approach

GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

Chlorine resistant TFN nanofiltration membrane incorporated with octadecylamine-grafted GO and fluorine-containing monomer

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