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Acoustic droplet vaporization (ADV) has shown a great potential in extravascular tumor-targeting theranostics. The mechanical perturbations produced during ADV process (e.g. initial volume expansion, cavitation, and movement of the bubble) on the nearby cells could cause cell dysfunction with irreversible cell membrane damage or facilitate drug delivery due to sonoporation. A confocal acousto-optical...
The phase transition of nanodroplet has great potential in localized therapy, e.g. gas embolotherapy, drug delivery and the extravascular tumor-targeted theranostics. To improve the temporal and spatial resolution and reduce the energy threshold of nanodroplet phase transition, photoacoustic cavitation (PAC) using synergistic laser and ultrasound was introduced and compared with acoustic droplet vaporization...
Acoustic droplet vaporization (ADV) has shown a great potential in extravascular tumor-targeting theranostics. During ADV, its mechanical effects on the nearby cells could cause cell dysfunction with irreversible cell membrane damage or facilitate drug delivery by sonoporation. Understanding the real-time characteristics and bio-effects of ADV on cells is significant to develop the approach in vivo...
The phase transition of nanodroplet has great potential in localized therapy, e.g. gas embolotherapy, drug delivery and the extravascular tumor-targeted theranostics. To improve the temporal and spatial resolution and reduce the energy threshold of nanodroplet phase transition, photoacoustic cavitation (PAC) using synergistic laser and ultrasound was introduced and compared with acoustic droplet vaporization...
Photodisruption can be used to generate microbubble or microbubbles in vivo, thus has potential as an important tool in theranostics. However, high laser intensity and extremely short pulse length in femtosecond, and thus the high cost limit its wide applications. In the study, photodisruption induced by nanosecond laser pulse in two liquid perfluorocarbons (PFCs), perfluoropentane (PFP) and perfluorohexane...
Laser induced optical breakdown (LIOB) or laser induced cavitation (LIC) in water has been investigated widely. Several patterns of LIC bubble are involved. However, LIOB in water needs relatively high laser intensity and extremely short pulse length in femtosecond. In the study, low intensity laser in nanoseconds was utilized in the LIOB in dodecafluoropentane (DDFP), and then the optical and acoustic...
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