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Functional ultrasound (fUS) is a novel technique for in vivo neuroimaging which allows to map subtle changes of the Cerebral Blood Volume (CBV) due to neurovascular coupling with a very high sensitivity, and thus map dynamics of brain activity [1]. In this study, we apply fUS to awake and behaving non-human primate to investigate the monitoring of saccadic eye movement by the supplementary eye field...
Functional ultrasound (fUS) imaging of the brain is a novel technique for in vivo neuroimaging which can acquire and map the cerebral blood volume (CBV) with a very high sensitivity. While fUS has demonstrated its ability to map cerebral activity through CBV subtle changes due to neurovascular coupling, [1], its temporal resolution has yet to be fully exploited. On the other hand, recent neuroscience...
3D functional imaging of the whole brain activity during visual task is a challenging task in rodents due to the complex tri-dimensional shape of involved brain regions and the fine spatial and temporal resolutions required to reveal the visual tract. By coupling functional ultrasound (fUS) imaging with a translational motorized stage and an episodic visual stimulation device, we managed to accurately...
The spatiotemporal study of the visual system of the rodent is a challenging area that conventional functional imaging modalities, despite fundamental achievements, still struggle to study nowadays. In the other hand Functional Ultrasound (fUS) offers an unprecedented combination of spatiotemporal resolution. By coupling fUS with an adapted visual stimulation device, we mapped the vision-evoked activity...
Large-scale functional imaging techniques are part of a fast growing field of neuroscience aiming at understanding whole brain activity. The recently introduced Functional Ultrasound Imaging (fUS), based on ultrafast Doppler, is a new very sensitive method monitoring changes in slow blood flow with a high spatial (∼100µm) and temporal (down to the cardiac time scale) resolution for a typical imaged...
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