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We describe the design, microfabrication, and testing of a microfluidic device for the separation of cancer cells based on dielectrophoresis. Cancer cells, specifically green fluorescent protein‐labeled MDA‐MB‐231, are successfully separated from a heterogeneous mixture of the same and normal blood cells. MDA‐MB‐231 cancer cells are separated with an accuracy that enables precise detection and counting...
In this work we describe the effect of Dielectrophoresis (DEP) on the deformation of red blood cells by measuring the change in aspect ratio. The force induced through DEP will act against the elastic force of the cell, lengthening and slimming the cell. The change in dimensions due to deformation under DEP is measured under a microscope, and when compared to DEP force applied, can provide useful...
In this paper, a simple method for cell dipping in a microfluidic device using dielectrophoresis is presented. A microfluidic system includes glass substrate and PDMS element is fabricated and tested. Cells dipping is performed and achieved using two sets of electrodes that slightly protrude into the microchannel through the sidewalls. The fabrication process and testing of the device are detailed.
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