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X-ray fluorescence CT (XFCT) imaging is a promising molecular imaging modality with high spatial resolution and non-radioactive high atomic number tracers for medical imaging. While dozens of bench-top experiments proofed the concept of the approach, scalability for clinical systems with high molecular sensitivity at acceptable doses is not yet accomplished. This study compares a spectroscopic CdTe...
XFCT is a promising new molecular imaging modality which is able to measure non-radioactive tracer molecules even in deep tissues. Unrestricted spatial resolution imaging with pencil beam x-ray excitation is possible but cannot be translated easily to clinical applications as scanning times are at least several hours. The spatial information accessed with Compton cameras (CCs) overcomes this drawback...
Cadmium zinc telluride (CZT) detectors are highly promising for advanced PET imaging due to their high energy and spatial resolution. In this contribution, an improved data analysis is suggested for the small animal PET system currently under construction at Stanford. Improved energy resolution in positron emission tomography (PET) helps to exclude scattered events and is necessary for new strategies...
The quadHIDAC is a dedicated high resolution small animal PET scanner based on multi-wire proportional chamber detectors. It provides very high spatial resolution, good sensitivity, and a large field-of-view allowing the examination of more than one animal in a single scan or a whole body scan of larger species in a single bed position. Excellent image quality has been obtained through list-mode-based...
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