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We control the motion of paramagnetic microparticles with average diameter of 100 µm inside microfluidic channels against and along time-varying flow rates. The drag force and the force due to time-varying flow rate are modeled as time-varying disturbance force. This force is estimated using a disturbance force observer and compensated using a magnetic-based closed-loop control system. The closed-loop...
We achieve selective penetration of MCF-7 breast cancer cells using iron-oxide nanoparticles without causing a permanent damage to the membrane and without any effect on the cell morphology. The nanoparticles are controllably pulled towards the cells under the influence of the magnetic field gradients. First, the nanoparticles are fabricated and their magnetic dipole moment is characterized to be...
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