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This paper reports the first electrolysis-based oxygen generation and transportation device for the treatment of retinal ischemia; containing an isolated biocompatible electrolyte and inductive power transfer for on-demand oxygen. A finite element model of the retina along with oxygen delivery data demonstrates the feasibility of the device. The estimated therapeutic window for the device was found...
For the first time, a paradigm shift in the treatment of retinal ischemia is proposed: providing localized supplemental oxygen to the ischemic tissue via an implanted MEMS device. A passive MEMS oxygen transporter is designed, built and tested in both artificial eye models and porcine cadaver eyes to confirm various hypotheses. The finite element modeling results predict that the proposed approach...
We report here a micro fluidic device with a controlled opening, which is used for accessing the fluid inside the micro channel from outside. The control of the reduced diameter of the opening pore is achieved by depositing a controlled Parylene layer on a starting lager opening hole. By changing the Parylene type and thickness, we can control the pore size and surface hydrophobicity. Due to the Laplace-Young's...
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