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Background The assembly of Next Generation Sequencing (NGS) reads remains a challenging task. This is especially true for the assembly of metagenomics data that originate from environmental samples potentially containing hundreds to thousands of unique species. The principle objective of current assembly tools is to assemble NGS reads into contiguous stretches of sequence called contigs while maximizing...
Next generation sequencing (NGS) has become the platform of numerous biomedical applications. The study of viral genomes using NGS technologies has led to the characterization of viral species in numerous environments including the human gut microbiome and plant hosts. Many viral genomes are circular or have terminally redundant ends. Circular or linear viral genomes with indeterminate starting and...
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