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Telepathology, the practice of pathology at a long distance, has advanced continuously since 1986. Today, almost 3 decades later, virtual slide telepathology has become a promising tool for providing re-review of surgical pathology cases as part of a quality assurance program but also for educational purposes. In this paper we present the Central Review for Pathology images platform (CRP), developed...
This paper investigates the applicability of multilevel macroscopic models for simulating solid tumor growth in the invasive glioblastoma multiforme (GBM) case. The continuum case approach tumor model based on the diffusion reaction equation is evaluated on a pre-segmented tomographic atlas where all tissue properties are known a priori. The atlas is further registered on a real clinical case where...
Several mathematical models have been developed to express glioma growth behavior. The most successful models have used the diffusion-reaction equation, with the most recent ones taking into account spatial heterogeneity and anisotropy. However, to the best of our knowledge, there hasn't been any work studying in detail the mathematical solution and implementation of the 3D diffusion model, addressing...
In the developed countries, healthcare systems are evolving under the pressure of the population ageing, the necessity of reducing the increasing healthcare costs and the availability of new technologies. Telemedicine and eHealth solutions are gaining importance in this reference frame. Recently we participated in the final validation phase of a wide European Project, Heartfaid, aimed at building...
The PhysioNet Challenge 2009 addresses the prediction of acute hypotensive episodes (AHEs), which are serious clinical events since they could result in multiple organ failure and eventually in death. This objective is pursued with two different events: (a) event 1: the separation of records with critical AHE (subgroup H1) in the forecast window (FW), the one-hour period immediately following a specified...
During the clinical validation of HEARTFAID, a platform of services for the medical-clinical management of heart failure (HF) in elderly subjects, performed in several European sites, special attention was paid to test Nurse@Home (N@H), a flexible and innovative application for the home monitoring of HF patients. This paper is focused on the validation performed in the sites of Catanzaro and Milan,...
Changes in heart rate (HR) and respiratory rate (RespR) may be used as markers of early decompensation in chronic heart failure (CHF) patients monitored at home. Aiming at improving quality of care and at reducing hospitalization rate and health care costs in CHF, progress in technology has led to the development of small portable and even wearable devices for the acquisition and transmission of relevant...
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