Search results for: Makoto Tamura

Items from 1 to 20 out of 25 results

article

Reimbursement pricing for new medical devices in Japan: Is the evaluation of innovation appropriate?

Makoto Tamura, Shohei Nakano, Takuma Sugahara

The International Journal of Health Planning and Management > 34 > 2 > 583 - 593

Objectives In Japan, strong reimbursement pricing control measures for existing medical device products have rendered new medical device reimbursement pricing critical for manufacturers. Few studies have been conducted on this aspect; therefore, this paper (1) clarifies whether evaluation of innovation is appropriate or not and (2), if not, investigates its background. Methods In this research,...

article

Global assessment of the effectiveness of adaptation in coastal areas based on RCP/SSP scenarios

Makoto Tamura, Naoko Kumano, Mizuki Yotsukuri, Hiromune Yokoki

Climatic Change > 2019 > 152 > 3-4 > 363-377

The objective of this study is to assess the global impact of sea level rise and to evaluate the effectiveness of adaptation. Global areas of inundation due to sea level rise are identified. The affected populations and the economic damage caused by inundation due to future climate change are estimated for a number of scenarios involving Representative Concentration Pathways (RCP) and Shared Socioeconomic...

article

Developing joint educational programs in sustainability science across different universities: a case study from Japan

Makoto Tamura, Motoharu Onuki, Makiko Sekiyama, Keishiro Hara, more

Sustainability Science > 2018 > 13 > 3 > 849-860

The challenge for sustainability educational programs lies in how to imbue students with the strong motivation necessary to move the world in a more sustainable direction. Five universities in Japan have mutually collaborated in the design and development of a unique curriculum and education system for sustainability science since 2008. Specifically, they have developed a common and remote lecture...

article

Seismicity controlled by resistivity structure: the 2016 Kumamoto earthquakes, Kyushu Island, Japan

Koki Aizawa, Hisafumi Asaue, Katsuaki Koike, Shinichi Takakura, more

Earth, Planets and Space > 2017 > 69 > 1 > 1-10

The M_JMA 7.3 Kumamoto earthquake that occurred at 1:25 JST on April 16, 2016, not only triggered aftershocks in the vicinity of the epicenter, but also triggered earthquakes that were 50–100 km away from the epicenter of the main shock. The active seismicity can be divided into three regions: (1) the vicinity of the main faults, (2) the northern region of Aso volcano (50 km northeast of the mainshock...

article

Association of Serum Fetuin-a with Aortic Stenosis in Patients Undergoing Hemodialysis

Wataru Mitsuma, Shoko Tsuchida, Katsuharu Hatada, Shunsuke Imai, more

Journal of Cardiac Failure > 2016 > 22 > 9(S) > S179

article

Developmental Inhibition of Gsk3 Rescues Behavioral and Neurophysiological Deficits in a Mouse Model of Schizophrenia Predisposition

Makoto Tamura, Jun Mukai, Joshua A. Gordon, Joseph A. Gogos

Neuron > 2016 > 89 > 5 > 1100-1109

While the genetic basis of schizophrenia is increasingly well characterized, novel treatments will require establishing mechanistic relationships between specific risk genes and core phenotypes. Rare, highly penetrant risk genes such as the 22q11.2 microdeletion are promising in this regard. Df(16)A^+/− mice, which carry a homologous microdeletion, have deficits in hippocampal-prefrontal connectivity...

article

Molecular Substrates of Altered Axonal Growth and Brain Connectivity in a Mouse Model of Schizophrenia

Jun Mukai, Makoto Tamura, Karine Fénelon, Andrew M. Rosen, more

Neuron > 2015 > 86 > 3 > 680-695

22q11.2 deletion carriers show specific cognitive deficits, and ∼30% of them develop schizophrenia. One of the disrupted genes is ZDHHC8, which encodes for a palmitoyltransferase. We show that Zdhhc8-deficient mice have reduced palmitoylation of proteins that regulate axonal growth and branching. Analysis of axonal projections of pyramidal neurons from both Zdhhc8-deficient and Df(16)A^+/− mice, which...

article

Reducing flood risks in rural households: survey of perception and adaptation in the Mekong delta

Frank Hiroshi Ling, Makoto Tamura, Kazuya Yasuhara, Kiyotake Ajima, more

Climatic Change > 2015 > 132 > 2 > 209-222

The Mekong Delta, one of the most vulnerable regions to climate change, is the focus of international action for adaptation. Improved understanding of the exposures and perceptions at the local level will help residents to cope with natural disasters and future climate disruptions. In this study, we assess the exposure to floods that rural communities across the Mekong Delta are facing. Among the...

chapter

A microfluidic static gradient generator using limited diffusuon through T-shaped narrow channels

Makoto Tamura, Shugo Maeda, Tomohisa Ogawa, Masato Tanaka, more

2014 International Symposium on Micro-NanoMechatronics and Human Science (MHS) > 1 - 4

2014 International Symposium on Micro-NanoMechatronics and Human Science (MHS)

We have developed a poly (dimethylsiloxane) (PDMS)-cast microfluidic chip that contains a thin (cross-sectional area less than 1.0 μm2) but high aspect ratio (1:1 ∼ 1:3) microchannels. Experimental results showed that the gradient of an example of test substances (sodium fluorescein) remained constant in the thin channel over a long period of time (30 minutes) by simple manual liquid handling. We...

article

Cuprizone short-term exposure: Astrocytic IL-6 activation and behavioral changes relevant to psychosis

Tomoaki Tezuka, Makoto Tamura, Mari A. Kondo, Masaki Sakaue, more

Neurobiology of Disease > 2013 > 59 > Complete > 63-68

A growing body of evidence suggests the involvement of inflammatory processes in the pathophysiology of schizophrenia. Four- to 8-week exposure to cuprizone, a copper chelator, causes robust demyelination and has been used to build a model for multiple sclerosis. In contrast, we report here the effects of 1-week cuprizone exposure in mice. This short-term cuprizone exposure elicits behavioral changes...

article

Development of an educational model for sustainability science: challenges in the Mind–Skills–Knowledge education at Ibaraki University

Makoto Tamura, Takahide Uegaki

Sustainability Science > 2012 > 7 > 2 > 253-265

Modern society confronts multiple sustainability challenges, including population growth, resources limitations, and a deteriorating environment. As a response, sustainability science education plays a major role in developing human capacity to manage these issues. This paper proposes the concept of “sustainability science education across Mind–Skills–Knowledge” as well as the competencies to be acquired...

article

Identifying the sources of energy use change: Multiple calibration decomposition analysis and structural decomposition analysis

Shinichiro Okushima, Makoto Tamura

Structural Change and Economic Dynamics > 2011 > 22 > 4 > 313-326

Decomposition methodologies are requisite to identify the sources of changes in energy use or carbon dioxide emissions. This paper is an inquiry into the theoretical properties of such decomposition methodologies. The study first presents our new decomposition methodology – the Multiple Calibration Decomposition Analysis (MCDA) – as a tool for the investigation. Then, it theoretically reexamines an...

article

Effects of climate change on coastal disasters: new methodologies and recent results

Kazuya Yasuhara, Hideo Komine, Hiromune Yokoki, Takeshi Suzuki, more

Sustainability Science > 2011 > 6 > 2 > 219-232

Humanity faces an increasing possibility that unusual and extreme natural disasters will increase, compounded with climate change, including global warming. These compound events are designated as compounded natural hazards in this study. A methodology must be developed for predicting what events and risks will confront future societies, to propose countermeasures and adaptation strategies against...

article

The role of technological change

Shinichiro Okushima, Makoto Tamura

Energy Economics > 2010 > 32 > Supplement 1 > S41-S46

This paper proposes a simple and theoretically clear approach to the estimation of technological change in a multisector general equilibrium framework. This study employs the Multiple Calibration Decomposition Analysis (MCDA) to evaluate technological change that is responsible for changes in energy use and carbon dioxide emissions in the Japanese economy in the oil crises period from 1970 to 1985...

article

Multiple bilateral coronary-biventricular fistulas with elevated left ventricular end-diastolic pressure

Masato Oda, Katsuharu Hatada, Kiminori Kato, Makoto Tamura, more

International Journal of Cardiology > 2009 > 134 > 1 > e26-e28

Arterioventricular fistulas are relatively rare abnormalities and the etiology may be congenital or traumatic. We report a case of a 51-year-old woman in which all three coronary arteries emptied into both ventricles via multiple small fistulas resulting in elevated left ventricular end-diastolic pressure.

article

A double calibration approach to the estimation of technological change

Shinichiro Okushima, Makoto Tamura

Journal of Policy Modeling > 2009 > 31 > 1 > 119-125

This paper suggests a new methodology for evaluating technological change in a multi-sector general equilibrium framework. The double calibration technique was applied to an ex post decomposition analysis of technological change between two periods, enabling a distinction to be made between price-induced and factor-biased technological changes for each sector. The method is applied to an empirical...

article

P3-o15 Prenatal stress impairs the dendritic maturation of dentate granule cells

Makoto Tamura, Akiyoshi Kakita, Norio Matsuki, Ryuta Koyama

Neuroscience Research > 2009 > 65 > Supplement 1 > S254-S255

article

Multiple calibration decomposition analysis: Energy use and carbon dioxide emissions in the Japanese economy, 1970–1995

Shinichiro Okushima, Makoto Tamura

Energy Policy > 2007 > 35 > 10 > 5156-5170

The purpose of this paper is to present a new approach to evaluating structural change of the economy in a multisector general equilibrium framework. The multiple calibration technique is applied to an ex post decomposition analysis of structural change between periods, enabling the distinction between price substitution and technological change to be made for each sector. This approach has the advantage...

article

Involvement of BDNF in mossy fiber fasciculation

Makoto Tamura, Naohiro Tamura, Ryuta Koyama, Yuji Ikegaya, more

Neuroscience Research > 2007 > 58 > Supplement 1 > S146

article

Photochemical Isomerization and X-ray Structure of Stable [Tris(trialkylsilyl)silyl]cyclotrisilene

Takeaki Iwamoto, Makoto Tamura, Chizuko Kabuto, Mitsuo Kira

Organometallics > 2003 > 22 > 11 > 2342 - 2344

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INFONA - science communication portal

Search results for: Makoto Tamura

Reimbursement pricing for new medical devices in Japan: Is the evaluation of innovation appropriate?

Global assessment of the effectiveness of adaptation in coastal areas based on RCP/SSP scenarios

Developing joint educational programs in sustainability science across different universities: a case study from Japan

Seismicity controlled by resistivity structure: the 2016 Kumamoto earthquakes, Kyushu Island, Japan

Association of Serum Fetuin-a with Aortic Stenosis in Patients Undergoing Hemodialysis

Developmental Inhibition of Gsk3 Rescues Behavioral and Neurophysiological Deficits in a Mouse Model of Schizophrenia Predisposition

Molecular Substrates of Altered Axonal Growth and Brain Connectivity in a Mouse Model of Schizophrenia

Reducing flood risks in rural households: survey of perception and adaptation in the Mekong delta

A microfluidic static gradient generator using limited diffusuon through T-shaped narrow channels

Cuprizone short-term exposure: Astrocytic IL-6 activation and behavioral changes relevant to psychosis

Development of an educational model for sustainability science: challenges in the Mind–Skills–Knowledge education at Ibaraki University

Identifying the sources of energy use change: Multiple calibration decomposition analysis and structural decomposition analysis

Effects of climate change on coastal disasters: new methodologies and recent results

The role of technological change

Multiple bilateral coronary-biventricular fistulas with elevated left ventricular end-diastolic pressure

A double calibration approach to the estimation of technological change

P3-o15 Prenatal stress impairs the dendritic maturation of dentate granule cells

Multiple calibration decomposition analysis: Energy use and carbon dioxide emissions in the Japanese economy, 1970–1995

Involvement of BDNF in mossy fiber fasciculation

Photochemical Isomerization and X-ray Structure of Stable [Tris(trialkylsilyl)silyl]cyclotrisilene

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