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The interwovenness of information technology and organizational structures suggests an understanding of organizations as systems of high complexity. The Viable Systems model (VSM), grounded on cybernetic principles, is a popular approach enabling researchers to assess the complexity of organizations heavily relying on information systems (IS). Although IS scholars have increasingly applied the VSM...
Astroglia is well-known to be integrated in the complex regulation of neuroinflammation in the central nervous system. Astrocytes become activated and synthesize cytokines, chemokines, and prostanoids during degenerative and vulnerable processes and interact with other immune-competent cells. Degenerative disorders often occur in a brain-region-specific fashion suggesting differences in the activity...
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