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Sarcopenia, described as the loss of muscle mass and/or strength, is gaining importance as it can be increasingly related to many chronic diseases. It is also associated with chronic liver disease, and recently it has been more frequently linked to non‐alcoholic fatty liver disease (NAFLD) in particular. Both sarcopenia and NAFLD are subject to complex and intermingled pathophysiological processes,...
Electrochemical anodization has been applied to grow 300 nm thick porous shell layers in 5 μm diameter silicon pillars. These pillars are positioned in a triangular grid with 2.5 μm spacing to form a pillar array columns (PAC) for liquid chromatography. The uniformity of the porous layer was assessed by determining local plate heights along the column length, which appeared to be constant. Minimal...
In the current contribution, it is demonstrated that radial elongation of support structures in a chromatographic column has an enormous impact on the axial band broadening occurring in the column. By increasing the lateral dimension of the support structures with respect to their axial dimension, axial band broadening could be reduced up to 5 times. For flat rectangular columns filled with 5 μm axial...
A Lab-on-Chip system is proposed, capable of SNP (Single Nucleotide Polymorphism) detection in DNA. One of the core components is an advanced filter consisting of an ordered array of Si micro-pillars enabling fast and effective separation of 5 DNA segments with different length using chromatographic techniques. Also a dedicated micro-pump is fabricated based on conductive polymer actuation, generating...
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