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In this work, we demonstrate the quantification of creatinine in human urine samples using a micro-calorimetric sensing system. The calorimetric sensor is based on an array of microfabricated Y-cut quartz resonators. The piezoelectric quartz is etched down to a thickness of 10 μm and exhibits a bulk acoustic resonance of 166 MHz. The temperature sensitivity of this high-frequency quartz resonator...
In this paper we report a calorimetrie sensing system for the detection of clinically relevant biomolecules. The calorimetrie biosensor consists of a thin (∼20 μm) micromachined Y-cut quartz crystal resonator (QCR) placed in close proximity to a fluidic chamber packed with an immobilized enzyme in alginate beads. This configuration enables a detection mechanism physically separated from the solution...
In this work, we have developed gas chromatography columns using microfabrication techniques and interfaced them using compression sealing technique to enable high temperature (∼400 °C) operation. Specifically, we present graphite compression sealing technique to achieve leak-proof fluidic interconnection between the inlet tubing and the microchannel, thus removing the limiting factor of epoxy and...
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