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We report on the design, assembly, and optical as well as thermal characterization of a polymer-based optrode with an integrated light source for applications in optogenetics. The novel probe allows to optically stimulate neural brain tissue in deeper brain regions and to simultaneously record brain activity using integrated macroelectrodes and microelectrodes. The optrode is based on a cylindrical...
This work reports on the design, assembly, and the optical as well as thermal properties of a polymer-based optrode with integrated light source to be appliedin optogenetic experiments. In parallel to electrical recordings of brain activity using macroelectrodes and microelectrodes, the enhanced depth probe enables the optical stimulation of neural tissue using integrated light emitting diodes (LEDs)...
Optical stimulation and inhibition of neural tissue is a promising neuroscientific method to control neural activity in so-called optogenetic experiments. This work illustrates the development of an implantable neural probe with an array of 10 integrated light emitting diode (μLED) chips emitting at a wavelength of 460 nm. The probe is suitable for experiments requiring a depth-controlled optical...
This paper reports on the design, simulation, fabrication and characterization of a tool for optogenetic experiments based on a light emitting diode (LED). A minimized silicon (Si) interface houses the LED and aligns it to an optical fiber. With a Si housing size of 550×500×380 μm3 and an electrical interconnection of the LED by a highly flexible polyimide (PI) ribbon cable is the system very variable...
This paper reports on the design, fabrication and characterization of an innovative silicon-based neural probe with optical functionality. This so-called optrode is intended as an ultracompact tool for optogenetic applications in neuroscientific research. Beside platinum microe-lectrodes for electrical recording applications, bare laser diode (LD) chips combined with waveguides (WGs) implemented in...
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