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Ultrasound shear wave imaging has been successfully developed with wide clinical applications. Typically, the shear wave image format is the same as the corresponding B-mode so that the shear modulus distribution can be overlaid with the anatomy. However, in certain applications the B-mode cross-sectional view may not be ideal. In this study, we propose a system for shear modulus computed tomography...
Simplex growing algorithm (SGA) is an endmember finding algorithm which grows simplexes one vertex at a time by finding vertexes which yield maximal simplex volumes via determinant calculation. This paper presents a new version of SGA, called orthogonal projection based simplex growing algorithm (OPSGA) which takes advantage of a simplex's geometric structure to calculate simplex volume by multiplying...
Small animal models have been used extensively in disease research, genomics research, drug development and developmental biology Non-invasive, small animal imaging with adequate spatial resolution and sensitivity is therefore beneficial to such research fields. In particular, multi-modality small animal imaging can provide complementary image information and is therefore of great interest. In this...
Synthetic aperture focusing using a virtual source was used previously to increase the penetration and to extend the depth of focus in high-frequency ultrasonic imaging. However, the performance of synthetic aperture focusing is limited by its high sidelobes. In this paper, an adaptive weighting technique based on a focusing-quality index is introduced to suppress the sidelobes. The focusing-quality...
Sound-velocity inhomogeneities degrade both spatial and contrast resolutions. This paper proposes a new adaptive imaging technique that uses the generalized coherence factor (GCF) to reduce the focusing errors resulting from the sound-velocity inhomogeneities. The GCF is derived from the spatial spectrum of the received aperture data after proper receive delays have been applied. It is defined as...
A new compounding technique for reducing speckle brightness variations is proposed. This method exploits the decorrelation between signals under different strain states. The different strain states can be created using externally applied forces such as the ones used in sonoelastography. Such forces produce three-dimensional tissue motion. By correcting only the in-plane (i.e., axial and lateral) motion,...
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