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In recent years, robot-assisted rehabilitation has gained momentum as a viable means for improving outcomes for therapeutic interventions. Such therapy experiences allow controlled and repeatable trials and quantitative evaluation of mobility metrics. Typically though these robotic devices have been focused on rehabilitation within a clinical setting. In these traditional robot-assisted rehabilitation...
This research investigates proper movement correlation as well as the overall perception of human subjects' interaction with a simulated agent and an embodied agent in a physical therapeutic scenario. Using computer vision techniques coupled with the Microsoft Kinect to quantify reaching kinematics, correlation was assessed by aliging movements with a Vicon Motion Capture System as well as determining...
The objective of this research effort is to advance the process of quantifying physical rehabilitation techniques by developing and validating the core technologies needed to integrate therapy instruction with human-robot interaction in order to improve upper-arm rehabilitation. The method presented uses computer vision techniques such as Motion History Imaging (MHI), edge detection, and Random Sample...
The Aristaless-related homeobox gene (ARX) is one of the major genes causing X-linked mental retardation. We have been interested in the pathogenic mechanism of expanded polyalanine tract mutations in ARX. We showed that the c.304ins(GCG) 7 mutation causing an increase from 16 to 23 alanines increased the propensity of ARX protein aggregation and a shift from nuclear to cytoplasmic localization...
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