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Background Accurate detection of polymorphisms with a next generation sequencer data is an important element of current genetic analysis. However, there is still no detection pipeline that is completely reliable. Result We demonstrate two new detection methods of polymorphisms focusing on the Polymorphic Edge (PED). In the matching between two homologous sequences, the first mismatched base to appear...
As the application of information system has been increasingly constructed in large enterprises and institutions, IT operation and maintenance have been developed into a integrated operation and maintenance system with multi-grade, multi-level and multi-control parameters, and its security level is difficult to be measured with a single indicator. On the basis of satisfying the dispatching and monitoring...
ICP (Iterative Closest Point) algorithm plays an important role in sequential scan matching SLAM. In the algorithm, closest point searching is the well-recognized speed bottleneck. We realize that a searching-friendly structure already exists in the raw data sequence from range acquisition device, and the acquisition order, which we called sensor order, is naturally derived from sensor working mechanism...
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