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Epidermal growth factor‐like domain‐containing protein 7 (EGFL7), a member of the epidermal growth factor (EGF)‐like protein family, is a potent angiogenic factor expressed in many different cell types. EGFL7 plays a vital role in controlling vascular angiogenesis during embryogenesis, organogenesis, and maintaining skeletal homeostasis. It regulates cellular functions by mediating the main signaling...
This article presents a new method for the data fusion of the intraoperative Electromyography (EMG) signals from a nerve monitor with the position information from a surgical navigation system. In principle, EMG signals and the position information are merged with each other based on the distance-threshold relationship. The merged information can be used to control the power of active surgical instruments...
This article describes the processing of computed tomography (CT) images with MATLAB for the fabrication of anatomically correct head phantoms. Such phantoms are applied for the verification of systems for image-guided interventions. For this purpose, a CT-image set of a patient's head has been read into MATLAB and the skin part (soft tissue between head and bone surface) and some bone parts were...
During the last few years, regional anesthesia using ultrasound imaging has increased dramatically in both clinical and research areas. This method provides a direct noninvasive imaging of the targeted nerve and the tissue around it in real time. Furthermore, it allows anesthetists to observe the injected anesthetics for optimal distribution. However, there are still some major limitations to this...
In order to prevent nerve injuries during ear-nose-throat (ENT) and skull base surgery, the method Navigated Control Functional is presented. Thereby, the power of active instruments is controlled based on position information, provided by a surgical navigation system, and nerve activity information, provided by a neurophysiologic monitoring system. Electrical stimulation is usually required for the...
This paper presents a new method Navigated Control Functional for protecting a nerve from damage during surgery. This method combines surgical navigation and realtime nerve activity measurement for power control of a surgical drill's motor. The power of a drill's motor is automatically reduced when the nerve activity is identified as critical or the drill reaches a predefined prohibited area. The...
In this article, a technical study of a new assistance system to support surgeons in milling on the temporal bone is presented. In particular, the overall accuracy of a new assistance system was investigated experimentally under conditions close to surgical practice. For the experiment, the assistance system has been used with its associated navigation system for ear-nose-throat (ENT) surgery. A specially...
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