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Senegalese sole (Solea senegalensis, Kaup) is a promising flatfish species in aquaculture. However, skeletal anomalies are still a great concern in sole farming. Investigation of this issue is crucial to improving larval quality and optimizing production. The aim of this study was to thoroughly assess anomalies in the rachis of reared sole at early developmental stages. Sole (n = 507) were sampled...
Advances in biotechnology have made possible the production of a large number of new proteins important to the food, pharmaceutical, and chemical industry. The significance of aqueous two-phase systems (ATPSs) in downstream processing with commercial application has been reported for the separation of a large number of biopharmaceutical products. For both industrial- and laboratory-scale purposes...
Senegalese sole (Solea senegalensis) is a flatfish of increasingly interest in aquaculture in recent years. The establishment of the production requires the determination of the optimal conditions for development, growth and welfare of the sole in tanks. One important problem in cultured Senegalese sole is the presence of skeletal malformations that alter the morphology of the fish and cause the consumer's...
Following the success of therapeutic recombinant proteins, monoclonal antibodies (mAbs) represent the second outbreak of innovation created by the biotechnology industry. With more than 25 products in clinical use worldwide, including eight blockbuster drugs, mAbs remain one of the most exciting and promising areas within the world pharmaceutical market, with a global share worth $55 billion in 2010...
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