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This study attempts to assess the quantitative potential of breast tomosynthesis imaging. Tomosynthesis might be a feasible replacement for digital mammography, so it is worthwhile to consider whether it can be quantitative like computed tomography (CT), where the image pixel values are expressed in Hounsfield units. For this investigation, plastic tissue-equivalent breast phantoms with 10 lesions...
Several studies have reported reprogramming of fibroblasts into induced cardiomyocytes; however, reprogramming into proliferative induced cardiac progenitor cells (iCPCs) remains to be accomplished. Here we report that a combination of 11 or 5 cardiac factors along with canonical Wnt and JAK/STAT signaling reprogrammed adult mouse cardiac, lung, and tail tip fibroblasts into iCPCs. The iCPCs were...
Breast cancer is the most common non-skin cancer and the second leading cause of cancer-related death in women here in the United States. Mammography is the current standard clinical imaging modality for breast cancer screening and diagnosis, and mammographic breast density (i.e. the percentage of the entire breast volume that is taken up by dense glandular tissue) has been shown to be a biomarker...
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