The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Model organisms are increasingly used to study and understand how neurofilament (NF)‐based neurological diseases develop. However, whether a NF homolog exists in C. elegans remains unclear. We characterize TAG‐63 as a NF‐like protein with sequence homologies to human NEFH carrying various coiled coils as well as clustered phosphorylation sites. TAG‐63 also exhibits features of NFL such as a molecular...
Kinesin‐3 UNC‐104(KIF1A) is the major axonal transporter of synaptic vesicles. Employing yeast two‐hybrid and co‐immunoprecipitation (Co‐IP) assays, we characterized a LIN‐2(CASK) binding site overlapping with that of reported UNC‐104 activator protein SYD‐2(Liprin‐α) on the motor's stalk domain. We identified the L27 and GUK domains of LIN‐2 to be the most critical interaction domains for UNC‐104...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.