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Prediction of protein structural classes is one of the most important and challenging tasks in the bioinformatics field. A protein is classified into one of the four main types of protein structural classes; all-??, all-??, ??/?? and ??+??. This paper investigates the role of amino acid indices (AAI) combined with traditional amino acid composition (AAC) to create a weighted amino acid composition...
There have been a number of techniques developed for the prediction of protein structural classes, however, they show various degrees of accuracies over different assessment procedures and, in particular, the role of sequence-driven-features (SDF) not rigorously investigated. Therefore, the aim of this study is to carry out the largest comprehensive and consistent investigation on approximately 1500...
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