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Platelet-rich plasma (PRP) is reported to promote collagen synthesis and cell proliferation as well as enhance cartilage repair. Our previous study revealed that the intracapsular injection of muscle derived stem cells (MDSCs) expressing bone morphogenetic protein 4 (BMP-4) combined with soluble Flt-1 (sFlt1) was effective for repairing articular cartilage (AC) after osteoarthritis (OA) induction...
Recent research showed that the majority of compatibility-breaking changes in a component-based, object-oriented software system are refactorings [5]. The software updating process in such system with the presence of heavily refactored application programming interface (API) is largely manual and disruptive to running, mission-critical applications, which are expected to run continuously without any...
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