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Background
Enfortumab vedotin (EV) is a novel antibody‐drug conjugate approved for advanced urothelial cancer (aUC) refractory to prior therapy. In the Urothelial Cancer Network to Investigate Therapeutic Experiences (UNITE) study, the authors looked at the experience with EV in patient subsets of interest for which activity had not been well defined in clinical trials.
Methods
UNITE was a retrospective...
Brain-Computer Music Interface (BCMI) is a new research area that is emerging at the cross roads of neurobiology, engineering sciences and music. This research involves three major challenging problems: the extraction of meaningful control information from signals emanating directly from the brain, the design of generative music techniques that respond to such information, and the training of subjects...
Acid-mediated ring-transformations of 5-alkylidene-2,5-dihydropyrrol-2-ones, available by cyclization of 1,3-diketone dianions with bis(imidoyl) dichlorides of oxalic acid, resulted in formation of functionalized pyran-4-ones, such as 5,6-dihydrobenzo[h]chromones and 5,6,7,8-tetrahydrochromones.
Generally speaking, information usually just gains significance only when it is being processed in the context of own experience and being linked to other information. This article describes the development of a generic model for an IT service catalog which could for instance be adapted and utilized by an IT provider in the field of a service management project. The fundamental idea for developing...
Oxygen isotope analyses of marine diatoms were performed in two independent ways. Stepwise fluorination of hydrous opal-A results in plateau δ 18 O values representing the isotopic composition of the silica frame oxygen. A method of controlled isotope exchange before silica dehydration also produces reliable results, although the exchangeability of the silica was variable. Consequently,...
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