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Cardiovascular effects of an essential oil from the aerial parts of Mentha x villosa (OEMV) were tested in rats using a combined in vivo and in vitro approach. In non-anesthetized normotensive rats, OEMV (1, 5, 10, 20, 30mgkg -1 body wt., i.v.) induced a significant and dose-dependent hypotension (-3+/-1.8%; -6+/-0.7%; -40+/-6.7%; -58+/-3.8%; -57+/-2.1%, respectively) associated with...