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In this study, we prepare and evaluate a novel cellbased micro-platform (microrobot) for active tumor therapy. The microrobots are fabricated utilizing the engulfment activity of immune cells (macrophages) with drug-loaded magnetic liposomes via phagocytosis. First, we synthesize magnetic nanoparticles (MNP) with superparamagnetic properties and high energy absorbance to near-infrared (NIR) light,...
Recently, bacteria-based microrobots (Bacteriobots), which consist of the microbeads as cargos of drugs, and attenuated bacteria as actuators and sensors, were proposed for cancer therapeutic microrbots. A new type of bacteriobots were prepared and investigated against tumors. The hyaluronic acid (HA) microbeads were crosslinked with divinyl sulfone (DVS) to form HA microbeads with diameter of 10...
This paper presents a novel mechanism and design of capsule endoscope in order to perform an active locomotive capsule endoscope (ALICE) robot integrated with micro-hydraulic pump for drug delivery function. The proposed locomotive capsule endoscope can actively move and investigate in gastrointestinal tract, powered externally by an electro-magnetic actuation (EMA) system. To perform a drug pumping...
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