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Since bacterial infection cause a significant economic loss in fish farms, it is necessary to develop rapid diagnostic tools. Interests on label‐free biosensors have been raised for the rapid detection of aquatic pathogenic bacteria but have not been extensively studied yet. Here we report a quartz crystal microbalance (QCM) immunosensor system for the rapid and simple detection of Aeromonas hydrophila...
Viral haemorrhagic septicaemia (VHS) is one of the most serious viral diseases damaging both fresh and marine fish species. VHS caused by VHSV and diagnosis of VHSV has been dependent on the conventional methods, such as cell culture and RT-PCR, which takes a few days or several hours. This study demonstrates a rapid and sensitive QCM biosensor for diagnosis of VHSV infection in fish. The QCM biosensor...
QCM technology offers a real time output, simplicity of use and cost effectiveness in addition to high sensitivity. Sensitivity of QCM immunosensor can be enhanced by improving the immobilisation procedure on the quartz surface. The immobilisation strategy should be able to control both the amount and the orientation of the antibody (immunoglobulin; IgG) on the transducer for high affinity to antigens...
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